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Rekombinanter Vimentin Antikörper (AA 366-466)

Der Maus Monoklonal anti-Vimentin Antikörper (Klon rVIM-6914) (ABIN7863498) detektiert spezifisch Vimentin in IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human.
Produktnummer ABIN7863498
639,45 €
Zzgl. Versandkosten 20,00 € und MwSt
Lieferung nach: Deutschland
Lieferung in 6 bis 10 Werktagen

Kurzübersicht für Rekombinanter Vimentin Antikörper (AA 366-466) (ABIN7863498)

Target

Alle Vimentin (VIM) Antikörper anzeigen
Vimentin (VIM)

Antikörpertyp

Recombinant Antibody

Reaktivität

  • 420
  • 159
  • 151
  • 73
  • 71
  • 53
  • 51
  • 50
  • 30
  • 30
  • 23
  • 19
  • 15
  • 13
  • 8
  • 6
  • 6
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 220
  • 182
  • 10
  • 7
  • 6
  • 5
  • 5
  • 2
Maus

Klonalität

  • 250
  • 186
Monoklonal

Konjugat

  • 269
  • 20
  • 15
  • 11
  • 11
  • 9
  • 6
  • 5
  • 5
  • 5
  • 5
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Vimentin Antikörper ist unkonjugiert

Applikation

  • 363
  • 181
  • 133
  • 114
  • 96
  • 83
  • 66
  • 47
  • 39
  • 35
  • 28
  • 28
  • 14
  • 6
  • 5
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (IHC)

Klon

RVIM-6914
  • Bindungsspezifität

    • 39
    • 32
    • 17
    • 16
    • 13
    • 12
    • 12
    • 11
    • 7
    • 7
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 366-466

    Verwendungszweck

    Recombinant Vimentin (Mesenchymal Cell Marker) Antibody

    Spezifität

    This MAb reacts with a 58 kDa protein identified as vimentin. It shows no cross-reaction with other closely related intermediate filament proteins (IFP s) such as desmin, keratin, neurofilament, and glial fibrillary acid protein.Anti-vimentin alone is of limited value as a diagnostic tool, however, when used in panels with other antibodies, it is useful for the sub-classification of a given tumor. Expression of vimentin, when used in conjunction with anti-keratin, is helpful when distinguishing melanomas from undifferentiated carcinomas and large cell lymphomas. All melanomas and Schwannomas react strongly with anti-vimentin. It labels a variety of mesenchymal cells, including melanocytes, lymphocytes, endothelial cells, and fibroblasts. Non-reactivity of anti-vimentin is often considered more useful than its positive reactivity, since there are a few tumors that do not contain vimentin, e.g. hepatoma and seminoma. Anti-vimentin is also useful as a tissue process control reagent.

    Aufreinigung

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    Immunogen

    Recombinant fragment (around aa366-466) of human Vimentin protein (exact sequence is proprietary)

    Isotyp

    IgG1, kappa
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    200 μg/mL

    Buffer

    Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C

    Informationen zur Lagerung

    Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    Haltbarkeit

    24 months
  • Target

    Vimentin (VIM)

    Andere Bezeichnung

    Vimentin

    Hintergrund

    VIM

    Human sarcomas ormelanomas.

    Molekulargewicht

    57-60kDa

    Gen-ID

    7431, 455493

    UniProt

    P08670

    Pathways

    Caspase Kaskade in der Apoptose
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