IL3RA Antikörper (AA 26-171)

Produktnummer ABIN7859670

Der Maus Monoklonal anti-IL3RA Antikörper wird verwendet zum Nachweis von IL3RA in Proben von Human, Maus, Ratte und Hamster. Er wurde validiert für WB.

Kurzübersicht für IL3RA Antikörper (AA 26-171) (ABIN7859670)

Target: IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

Reaktivität: Human, Maus, Ratte, Hamster

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IL3RA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: IL3RA-1822

Produktdetails anti-IL3RA Antikörper

Bindungsspezifität: AA 26-171

Verwendungszweck: IL3RA / CD123 (Acute Myeloid Leukemia Marker) Antibody

Spezifität: CD123 is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudo-autosomal region on chromosomes X or Y.

Aufreinigung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment of human IL3RA protein (around aa 26-171) (exact sequence is proprietary)

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu IL3RA

Target: IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

Andere Bezeichnung: IL3RA

Hintergrund:

CD123, hIL3Ra, IL-3R-alpha, IL-3RA, IL3RAX, IL3RAY, IL3RX, IL3RY, Interleukin-3 Receptor, alpha, Interleukin3 receptor, Interleukin3 receptor, Y-chromosomal

Lymph Node or Stomach., RPMI-8226 or HDLM-2 cells. Tonsil, THP-1

Molekulargewicht: 70kDa

Gen-ID: 3563, 632790

UniProt: P26951

Pathways: JAK-STAT Signalweg