Thrombospondin 1 Antikörper (AA 200-400)
Kurzübersicht für Thrombospondin 1 Antikörper (AA 200-400) (ABIN7859517)
Target
Alle Thrombospondin 1 (THBS1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 200-400
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Verwendungszweck
- Thrombospondin-1 / THBS1 Antibody
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Spezifität
- The thrombospondin proteins (TSP 1-4) compose a family of glycoproteins that are involved in cell-to-cell and cell-to-matrix signaling. These extracellular, cell surface proteins form complexes of both homo- and heteromultimers. Thrombospondins play a role in development, aggregation of platelets, adhesion and migration of cells, and progression of cells through the growth cycle. Thrombospondin 1 is released from platelets in response to Thrombin stimulation and is a transient component of the extracellular matrix of developing and repairing tissues. Thrombospondin 2 shares a high degree of homology with Thrombospondin 1 and is thought to have overlapping but unique functions. Thrombospondin 3 is a developmentally regulated heparin binding protein. Thrombospondin 4 is neuronally expressed and stimulates neurite outgrowth.
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Aufreinigung
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogen
- Recombinant fragment (around aa 200-400) of human THBS1 protein (exact sequence is proprietary)
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Isotyp
- IgG1, kappa
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS
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Konservierungsmittel
- Azide free
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- Thrombospondin 1 (THBS1)
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Andere Bezeichnung
- Thrombospondin-1
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Hintergrund
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Thbs1, Thrombospondin-1, TSP, Tsp1, TSP1_HUMAN
Human lymph node|spleen|stomach or colon.
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Molekulargewicht
- ~165-198kDa
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Gen-ID
- 7057, 164226
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UniProt
- P07996
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Pathways
- Autophagie
Target
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