LAMP1 Antikörper (AA 200-400)

Produktnummer ABIN7859481

Der Maus Monoklonal anti-LAMP1 Antikörper wird verwendet zum Nachweis von LAMP1 in Proben von Human. Er wurde validiert für IHC.

Kurzübersicht für LAMP1 Antikörper (AA 200-400) (ABIN7859481)

Target: LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser LAMP1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: LAMP1-7457

Produktdetails anti-LAMP1 Antikörper

Bindungsspezifität: AA 200-400

Verwendungszweck: CD107a / Lysosomal associated membrane protein 1 (LAMP1) Antibody

Spezifität: Lysosome-associated membrane proteins (LAMP) are glycosylated type I membrane proteins that play a role in the biogenesis of the pigment melanin. LAMP-1 (also designated CD107a) and LAMP-2 (also designated CD107b) are involved in a variety of functions, including cellular adhesion, and are thought to participate in the process of tumor invasion and metastasis. Newly synthesized LAMP-1 and LAMP-2 proteins are sorted at the trans-Golgi network and are transported intracellularly via a pathway that is distinct from the Clathrincoated vesicles used for the mannose-6 phosphate receptor. LAMP-1 is expressed on the surface of Thrombin-activated but not resting platelets, and it is thought to be involved in the adhesive, prothrombic properties of these cells. Both LAMP-1 and LAMP-2 are involved in maintaining lysosome acidity and protecting the lysosomal membranes from autodigestion, and their expression is increased in patients with lysosomal storage disorders.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa200-400) of human LAMP1 protein (exact sequence is proprietary)

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Details zu LAMP1

Target: LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

Andere Bezeichnung: CD107a

Hintergrund:

CD107 antigen like family member A, LAMP1, LAMPA, LGP120, lgpA, Lysosomal membrane glycoprotein 120KD, Lysosomal Associated Membrane Protein 1, Lysosome associated membrane glycoprotein 1, OTTHUMP00000040663

Human tonsil|kidney or prostate.|Placenta

Molekulargewicht: 120 kDa

Gen-ID: 3916, 494419

Pathways: Autophagie