Galectin 9 Antikörper (AA 200-355)

Produktnummer ABIN7859445

Der Maus Monoklonal anti-Galectin 9 Antikörper wird verwendet zum Nachweis von Galectin 9 in Proben von Human. Er wurde validiert für IHC.

Kurzübersicht für Galectin 9 Antikörper (AA 200-355) (ABIN7859445)

Target: Galectin 9 (LGALS9) (Lectin, Galactoside-Binding, Soluble, 9 (LGALS9))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Galectin 9 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: LGALS9-7689

Produktdetails anti-Galectin 9 Antikörper

Bindungsspezifität: AA 200-355

Verwendungszweck: Galectin-9 (LGALS9) (Marker of T-Cell Exhaustion) Antibody

Spezifität: Galectins are a family of soluble ≤-galactoside-binding animal lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. One member of this family, Galectin-9, also known as Ecalectin, Gal-9, hUAT2, HOM-HD-21 or LGALS9, maps to human chromosome 17 and encodes a 36 kDa protein. Galectin-9 is an integral membrane protein that exists as two isoforms, a long form and a short form, which differ by an internal stretch of 32 amino acids. Galectin-9 is an eosinophile chemoattractant produced by activated T lymphocytes that is expressed in organs of the gastrointestinal tract, aorta, liver, kidney, liver, pancreatic islets, lung, tonsil and some colorectal carcinoma, and in the cell lines HUVEC, U-937, HL60, HeLa and Jurkat. Introduction of IL-1beta enhances Galectin-9 expression. Increased expression of Galectin-9 induces apoptosis in thymocytes and CD8+ cells. Galectin-9 is involved in immuno/inflammation processes in potential-sensitive uric acid translocation and contributes to inflammatory reactions in the central nervous system (CNS).

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa200-355) of human LGALS9 protein (exact sequence is proprietary)

Isotyp: IgG2, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Details zu Galectin 9

Target: Galectin 9 (LGALS9) (Lectin, Galactoside-Binding, Soluble, 9 (LGALS9))

Andere Bezeichnung: Galectin-9

Hintergrund:

Gal-9 | LGALS9

Human lung, liver, breast or kidney.

Molekulargewicht: 36kDa

Gen-ID: 3965

UniProt: O00182