Rekombinanter PD-L1 Antikörper (AA 190-290)
Kurzübersicht für Rekombinanter PD-L1 Antikörper (AA 190-290) (ABIN7859322)
Target
Alle PD-L1 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 190-290
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Verwendungszweck
- Recombinant PD-L1 / PDCD1LG1 / CD274 / B7-H1 (Cancer Immunotherapy Target) Antibody
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Spezifität
- PD-L1 is a checkpoint regulator in immune cells, it is expressed on immune or non-hematopoietic cells. Expression of the protein is seen during pregnancy where it has a role in suppressing the immune system. PD-L1 induces an inhibitory signal in activated T-cells and promotes T-cell apoptosis. It is overexpressed in a number of different cancers where it is believed to play a significant role in the cancer s ability to evade the immune system.
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Aufreinigung
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogen
- Recombinant fragment (around aa190-290) of human CD274 protein (exact sequence is proprietary)
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Isotyp
- IgG, kappa
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anti-CD274 (PD-L1) (C-Term) antibody
Verified PD-L1 Reaktivität: Human WB, FACS, ELISA, IF Wirt: Ziege Polyclonal unconjugated
anti-CD274 (PD-L1) (C-Term) antibodyPD-L1 Reaktivität: Human WB, FACS, IHC, IP, IF (p), IF/ICC, mIF Wirt: Kaninchen Monoclonal BLR020E unconjugated Recombinant Antibody
anti-CD274 (PD-L1) (AA 39-191) antibodyPD-L1 Reaktivität: Human, Maus WB, FACS, IHC, ELISA, IF Wirt: Maus Monoclonal PDL1-2746 unconjugated
anti-CD274 (PD-L1) (AA 19-238) antibodyPD-L1 Reaktivität: Human WB, FACS, IHC, ELISA, IF Wirt: Maus Monoclonal 9B5F4 unconjugated
anti-CD274 (PD-L1) (AA 24-153) antibodyPD-L1 Reaktivität: Human FACS, IHC, ELISA Wirt: Maus Monoclonal 6D9A2 unconjugated
anti-CD274 (PD-L1) (AA 48-290) antibodyPD-L1 Reaktivität: Maus WB, IHC, ICC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-CD274 (PD-L1) (AA 34-241) antibodyPD-L1 Reaktivität: Maus WB, IHC, ICC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-CD274 (PD-L1) (AA 24-153) antibodyPD-L1 Reaktivität: Human FACS, ELISA Wirt: Maus Monoclonal 7D2A10 unconjugated
anti-CD274 (PD-L1) (C-Term) antibodyKO Validated PD-L1 Reaktivität: Human WB, FACS, ICC, IF, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-CD274 (PD-L1) (AA 24-234) antibodyPD-L1 Reaktivität: Human WB, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS
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Konservierungsmittel
- Azide free
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Haltbarkeit
- 24 months
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- PD-L1 (CD274 (PD-L1))
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Andere Bezeichnung
- PD-L1
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Hintergrund
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B7 homolog 1, B7-H1, CD274, PD-L1, PDCD1 ligand 1, PDCD1L1, PDCD1LG1, Programmed cell death 1 ligand 1
Human placenta|spleen or tonsil tissue. Kidney, lung, Raji
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Molekulargewicht
- 37-50kDa
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Gen-ID
- 29126, 521989
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UniProt
- Q9NZQ7
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Pathways
- Cancer Immune Checkpoints
Target
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