Reelin Antikörper (AA 1796-2115)

Produktnummer ABIN7862732

Dieser Maus Monoklonal Antikörper detektiert spezifisch Reelin in WB, IHC, ELISA und IF. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Nagetiere.

Kurzübersicht für Reelin Antikörper (AA 1796-2115) (ABIN7862732)

Target: Reelin (RELN)

Reaktivität: Human, Maus, Nagetiere

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Reelin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Klon: RELN-4498

Produktdetails anti-Reelin Antikörper

Bindungsspezifität: AA 1796-2115

Verwendungszweck: Reelin Antibody

Spezifität: Reelin (or Reln) is a large glycoprotein that is secreted by Cajal-Retzius cells in the forebrain and by granule neurons in the cerebellum. Reelin was shown to be mutated in reeler mice, a mutation that is associated with widespread disruption of laminated regions of the brain, leading to impaired motor coordination, tremors and ataxia. Reelin protein expression is complex and changes throughout development. Reelin appears to function upstream of Dab1, in a signaling pathway that controls cell positioning in the developing brain, and is also thought to be a direct effector of the neurotrophin BDNF.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa 1796-2115) of human RELN protein

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu Reelin

Target: Reelin (RELN)

Andere Bezeichnung: Reelin

Hintergrund:

LIS2, PRO1598, Reeler, Reelin, RELN, RELN_HUMAN, RL

Human or mouse brain or CNS.

Molekulargewicht: 387.5kDa

Gen-ID: 19699, 655654

UniProt: P78509

Pathways: Synaptic Membrane