SULT1E1 Antikörper (AA 100-294)
Kurzübersicht für SULT1E1 Antikörper (AA 100-294) (ABIN7858989)
Target
Alle SULT1E1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 100-294
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Verwendungszweck
- Sulfotransferase family 1E, estrogen-preferring, member 1 Antibody
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Spezifität
- The soluble sulfotransferases contribute to the elimination of xenobiotics, the activation of procarcinogens and the regulation of hormones by catalyzing the sulfate conjugation of these substances. SULT1E1, also known as STE, is a 294 amino acid member of the SULT1 family. Localized to the cytoplasm and expressed in intestine, liver and kidney, SULT1E1 exists as a homodimer that is thought to control estrogen receptor (ER) levels by sulfurylating free estradiol. Defects in the gene encoding SULT1E1 are associated with an increased risk for endometrial cancer, suggesting a role for SULT1E1 in tumorigenesis.
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Aufreinigung
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogen
- Recombinant fragment (around aa100-294) of human SULT1E1 protein (exact sequence is proprietary)
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Isotyp
- IgG2, kappa
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS
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Konservierungsmittel
- Azide free
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- SULT1E1 (Sulfotransferase Family 1E Member 1 (SULT1E1))
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Andere Bezeichnung
- Sulfotransferase family 1E, estrogen-preferring, member 1
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Hintergrund
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EST, EST-1,EST1, Estrogen sulfotransferase, estrogen-preferring, estrone sulfotransferase, ST1E1, STE, Sulfotransferase 1E1, Sulfotransferase , Sulfotransferase estrogen preferring
HEPG2 cells. Human liver|intestine or kidney.
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Molekulargewicht
- 35kDa
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Gen-ID
- 6783, 479898
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UniProt
- P49888
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Pathways
- Steroid Hormone Biosynthesis
Target
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