ACE2 Antikörper (AA 1-300)

Produktnummer ABIN7858808

Dieser Maus Monoklonal Antikörper detektiert spezifisch ACE2 in WB, IHC und ELISA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für ACE2 Antikörper (AA 1-300) (ABIN7858808)

Target: ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ACE2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Klon: ACE2-7203

Produktdetails anti-ACE2 Antikörper

Bindungsspezifität: AA 1-300

Verwendungszweck: ACE2 / Angiotensin I Converting Enzyme 2 Antibody

Spezifität: Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II toangiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. By cleavage ofangiotensin II, may be an important regulator of heart function. By cleavage of angiotensin II, may also have a protective role in acute lung injury. Plays an important role in amino acid transport by acting as binding partner of amino acid transporter SL6A19 in intestine, regulating trafficking, expression on the cell surface, and its catalytic activity In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa1-300) of human ACE2 (exact sequence is proprietary)

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Details zu ACE2

Target: ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

Andere Bezeichnung: ACE2

Hintergrund:

ACE related carboxypeptidase, ACE2, ACEH, Angiotensin converting enzyme 2, Angiotensin converting enzyme like protein, Angiotensin I Converting Enzyme (peptidyl dipeptidase A) 2, Angiotensin-converting enzyme homolog, EC 3.4.17, DKFZP434A014, Metalloprotease MPROT15, Processed angiotensin-converting enzyme 2

Heart|Human kidney|testis or small intestine.

Molekulargewicht: 92kDa

Gen-ID: 59272, 178098

UniProt: Q9BYF1

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour