Rekombinanter OLIG2 Antikörper (AA 1-200)

Produktnummer ABIN7858638

Der Kaninchen Monoklonal anti-OLIG2 Antikörper wird verwendet zum Nachweis von OLIG2 in Proben von Human. Er wurde validiert für IHC.

Kurzübersicht für Rekombinanter OLIG2 Antikörper (AA 1-200) (ABIN7858638)

Target: OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser OLIG2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: OLIG2-9995R

Produktdetails anti-OLIG2 Antikörper

Bindungsspezifität: AA 1-200

Verwendungszweck: Recombinant OLIG2 (Marker of Glial Brain Tumors) Antibody

Spezifität: Olig2, a basic helix-loop-helix transcription factor, is involved in oligo-dendroglial specification. Olig2 expression has been reported in most glial tumors, such as oligodendrogliomas and astrocytomas. Although more than half of glioblastomas are positive for Olig2, expression is very weak in terms of both percentage of labeled cells and intensity. No Olig2 expression has been found in the non-glial tumors including neuroepithelial tumors, ependymomas, sub-ependymomas, medulloblastomas, and non-neuroepithelial tumors, such as CNS lymphomas, meningiomas, schwannomas, atypical teratoid/rhabdoid tumor, and haemangioblastomas. Compared to the strong staining seen in glioma samples, a weak expression is observed in non-tumoral brain tissue.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa1-200) of human OLIG2 protein (exact sequence is proprietary)

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu OLIG2

Target: OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))

Andere Bezeichnung: OLIG2

Hintergrund:

Basic helix loop helix protein class B1 (bHLHB1), basic helix-loop-helix protein 19 (bHLHe19), OLIG2, Oligodendrocyte lineage transcription factor 2, Oligodendrocyte specific bHLH transcription factor 2, Oligodendrocyte transcription factor 2, Protein kinase C-binding protein 2 (PRKCBP2), RACK17

THP-1 cells. Human brain or astrocytoma.

Molekulargewicht: 32kDa

Gen-ID: 10215, 176977

UniProt: Q13516