OLIG2 Antikörper (N-Term)

Produktnummer ABIN2777314

Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-OLIG2 Antikörper wird verwendet zum Nachweis von OLIG2 in Proben von Human, Maus, Ratte, Zebrafisch (Danio rerio), Meerschweinchen, Hund und Pferd. Er wurde validiert für WB und IHC.

Kurzübersicht für OLIG2 Antikörper (N-Term) (ABIN2777314)

Target: OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Meerschweinchen, Hund, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser OLIG2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-OLIG2 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: OLIG2 Antibody - N-terminal region

Sequenz: MDSDASLVSS RPSSPEPDDL FLPARSKGSS GSAFTGGTVS SSTPSDCPPE

Homologie: Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against OLIG2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human OLIG2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP31464-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-OLIG2 Antikörper (ABIN2777314)

Mitkus, Hyde, Vakkalanka, Kolachana, Weinberger, Kleinman, Lipska: "Expression of oligodendrocyte-associated genes in dorsolateral prefrontal cortex of patients with schizophrenia." in: Schizophrenia research, Vol. 98, Issue 1-3, pp. 129-38, (2007) (PubMed).

Details zu OLIG2

Target: OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))

Andere Bezeichnung: OLIG2

Hintergrund:

Background Information: OLIG2 is a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. OLIG2 is an essential regulator of ventral neuroectodermal progenitor cell fate. It is associated with T-cell acute lymphoblastic leukemia due to a chromosomal translocation t(14,21)(q11.2,q22). OLIG2 might play a role in learning deficits associated with Down syndrome.This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14,21)(q11.2,q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Oligodendrocyte lineage transcription factor 2

Alternative Symbols: BHLHB1, OLIGO2, RACK17, PRKCBP2, bHLHe19

Protein Name: Oligodendrocyte transcription factor 2

Molekulargewicht: 32kDa

Gen-ID: 10215

NCBI Accession: NP_005797

UniProt: Q13516