Interferon gamma Antikörper (AA 1-166)

Produktnummer ABIN7858304

Dieser Maus Monoklonal Antikörper detektiert spezifisch Interferon gamma in IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Interferon gamma Antikörper (AA 1-166) (ABIN7858304)

Target: Interferon gamma (IFNG)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Interferon gamma Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: IFNG-9012

Produktdetails anti-Interferon gamma Antikörper

Bindungsspezifität: AA 1-166

Verwendungszweck: Interferon gamma (IFNG) Antibody

Spezifität: Recognizes a protein of 20-25 kDa, identified as human interferon. This MAb is specific to human IFN-≥ and recognizes both recombinant and native human IFN-gamma. T lymphocytes and NK cells mainly produce IFN-≥. It is a pleiotropic cytokine involved in the regulation of nearly all phases of immune and inflammatory responses, including the activation, growth and differentiation of T cell, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. It has weak anti-viral and anti-proliferative activity, and potentiates the antiviral and anti-tumor effects of IFN-±/≤ (type I interferon).

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa1-166) of human IFNG protein (exact sequence is proprietary)

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Details zu Interferon gamma

Target: Interferon gamma (IFNG)

Andere Bezeichnung: Interferon gamma

Hintergrund:

AMCF1, Beta thromboglobulin like protein, CXC chemokine ligand 8 (CXCL8), Emoctakin, Granulocyte chemotactic protein 1 (GCP1), IFG, IFI, IFN Immune, IFN-gamma (IFNG), Interleukin 8, Interferon gamma, LECT, LUCT, Lymphocyte derived neutrophil activating factor, LYNAP, Macrophage Activating Factor (MAF), Monocyte derived neutrophil activating protein (MONAP), Monocyte derived neutrophil chemotactic factor (MDNCF), Neutrophil activating factor (NAF), Neutrophil activating peptide 1 (NAP1), Neutrophil activating protein 1 (NAP1), SCYB8, T cell chemotactic factor, T Cell Interferon

Human renal or testicular carcinoma.

Molekulargewicht: 20-25kDa

Gen-ID: 3458, 856

UniProt: P01579

Pathways: Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagie