Rekombinanter Podoplanin Antikörper (AA 1-100)

Produktnummer ABIN7858125

Der Maus Monoklonal anti-Podoplanin Antikörper wird verwendet zum Nachweis von Podoplanin in Proben von Human. Er wurde validiert für WB und IHC.

Kurzübersicht für Rekombinanter Podoplanin Antikörper (AA 1-100) (ABIN7858125)

Target: Podoplanin (PDPN)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Podoplanin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Klon: RPDPN-6994

Produktdetails anti-Podoplanin Antikörper

Bindungsspezifität: AA 1-100

Verwendungszweck: Recombinant Podoplanin (PDPN) (Lymphatic Endothelial & Mesothelial Marker) Antibody

Spezifität: It recognizes a muco-protein of 38-43 kDa, which is identified as Podoplanin (PDPN). It localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes. It is selectively expressed in lymphatic endotheliumÇ 79oΩas well as lymphoangiomas,Ç 79oΩKaposi sarcomas,Ç 79oΩand in a subset of angiosarcomas with probable lymphatic differentiation. Recent studies have also shown podoplanin to be a highly sensitive and relatively specific marker for epithelioid mesothelioma. Therefore, it can be used in a panel to distinguish mesotheliomas or mesothelial cells from pulmonary carcinomas.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant human Podoplanin (PDPN) protein fragment (around aa 1-100) (exact sequence is proprietary)

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu Podoplanin

Target: Podoplanin (PDPN)

Andere Bezeichnung: Podoplanin

Hintergrund:

Aggrus, Glycoprotein 36 KD, Glycoprotein 36, gp36, GP38, GP40, HT1A1, hT1alpha1, hT1alpha2, Lung type I cell membrane associated glycoprotein, Lung type I cell membrane associated glycoprotein T1A 2, OTS8,

HeLa cells. Human cervical or lung carcinoma.

Molekulargewicht: 38-43kDa

Gen-ID: 10630, 468675

UniProt: Q86YL7

Pathways: Dicarboxylic Acid Transport