Rekombinanter Androgen Receptor Antikörper (AA 1-100)
Kurzübersicht für Rekombinanter Androgen Receptor Antikörper (AA 1-100) (ABIN7858053)
Target
Alle Androgen Receptor (AR) Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 1-100
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Verwendungszweck
- Recombinant Androgen Receptor (Marker of Androgen Dependence) Antibody
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Spezifität
- Androgen Receptor is a member of the superfamily of ligand responsive transcription regulators. The androgen receptor functions in the nucleus where it is believed to act as a transcriptional regulator mediating the action of male sex hormones. The androgen receptor has wide distribution and can be demonstrated by immunohistochemistry in several tissues including prostate, skin, and oral mucosa. Androgen receptor has been reported in a diverse range of human tumors including osteosarcoma, and in prostatic carcinoma androgen receptor expression may be of clinical relevance.
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Aufreinigung
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogen
- Synthetic peptide corresponding to residues (within aa 1-100) of human Androgen Receptor.
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Isotyp
- IgG, kappa
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS
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Konservierungsmittel
- Azide free
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Haltbarkeit
- 24 months
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- Androgen Receptor (AR)
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Andere Bezeichnung
- Androgen Receptor
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Hintergrund
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AIS, Dihydrotestosterone receptor (DHTR), HUMARA, HYSP1, Kennedy disease (KD), Nuclear receptor subfamily 3 group C member 4 (NR3C4), SMAX1, Spinal and bulbar muscular atrophy (SBMA), Testicular Feminization (TFM)
Breast|LNCap cells. Human testis|prostate or prostate carcinoma. MCF7
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Molekulargewicht
- 110kDa
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Gen-ID
- 367, 496240
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UniProt
- P10275
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Pathways
- Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding
Target
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