Rekombinanter Uroplakin 2 Antikörper (AA 36-51)

Produktnummer ABIN7858042

Der Kaninchen Monoklonal anti-Uroplakin 2 Antikörper (Klon UPK2-13348R) (ABIN7858042) detektiert spezifisch Uroplakin 2 in IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Rekombinanter Uroplakin 2 Antikörper (AA 36-51) (ABIN7858042)

Target: Uroplakin 2 (UPK2)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Uroplakin 2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: UPK2-13348R

Produktdetails anti-Uroplakin 2 Antikörper

Bindungsspezifität: AA 36-51

Verwendungszweck: Recombinant Uroplakin II (UPK2) (Urothelial Differentiation Marker) Antibody

Spezifität: Uroplakin II (UPII) is a 15- kDa protein comprising urothelial plaques, which fortify the urothelial barrier. It is a highly specific marker for tumors of urothelial origin, particularly urothelial carcinoma (UC). UPII messenger RNA has been detected in the tissue and blood of UC patients. Immunohistochemistry utilizing UPII antibodies, such as UPK2/13669R, exhibits high specificity and increased sensitivity for urothelial carcinoma compared to UPIII antibodies. UPII immunohistochemistry is valuable for differentiating urothelial carcinoma from other malignancies, including prostate adenocarcinoma or metastatic breast carcinoma. It has also shown promise for detecting micrometastases of bladder cancer. UPII expression is found in various UC subtypes like micro-papillary, plasmacytoid, and sarcomatoid variants.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A.

Immunogen: Recombinant fragment (around aa 36-51) of human Uroplakin 2 (UPK2) protein (exact sequence is proprietary)

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu Uroplakin 2

Target: Uroplakin 2 (UPK2)

Andere Bezeichnung: Uroplakin II

Hintergrund:

UP2, UPII

Urinary bladder.

Molekulargewicht: 195kDa

Gen-ID: 7379

UniProt: O00526