Rekombinanter Uroplakin 2 Antikörper (AA 36-51)

Produktnummer ABIN7858041

Der Kaninchen Monoklonal anti-Uroplakin 2 Antikörper wird verwendet zum Nachweis von Uroplakin 2 in Proben von Human. Er wurde validiert für IHC.

Kurzübersicht für Rekombinanter Uroplakin 2 Antikörper (AA 36-51) (ABIN7858041)

Target: Uroplakin 2 (UPK2)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Uroplakin 2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: UPK2-13669R

Produktdetails anti-Uroplakin 2 Antikörper

Bindungsspezifität: AA 36-51

Verwendungszweck: Recombinant Uroplakin II (UPK2) (Urothelial Differentiation Marker) Antibody

Spezifität: Uroplakin II (UPII) is a 15- kDa protein comprising urothelial plaques, which fortify the urothelial barrier. It is a highly specific marker for tumors of urothelial origin, particularly urothelial carcinoma (UC). UPII messenger RNA has been detected in the tissue and blood of UC patients. Immunohistochemistry utilizing UPII antibodies, such as UPK2/13669R, exhibits high specificity and increased sensitivity for urothelial carcinoma compared to UPIII antibodies. UPII immunohistochemistry is valuable for differentiating urothelial carcinoma from other malignancies, including prostate adenocarcinoma or metastatic breast carcinoma. It has also shown promise for detecting micrometastases of bladder cancer. UPII expression is found in various UC subtypes like micro-papillary, plasmacytoid, and sarcomatoid variants.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A.

Immunogen: Recombinant fragment (around aa 36-51) of human Uroplakin 2 (UPK2) protein (exact sequence is proprietary)

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu Uroplakin 2

Target: Uroplakin 2 (UPK2)

Andere Bezeichnung: Uroplakin II

Hintergrund:

UP2, UPII

Urinary bladder.

Molekulargewicht: 195kDa

Gen-ID: 7379

UniProt: O00526