IL-10 Antikörper

Produktnummer ABIN7858009

Der Maus Monoklonal anti-IL-10 Antikörper (Klon IL10-8711) (ABIN7858009) detektiert spezifisch IL-10 in IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für IL-10 Antikörper (ABIN7858009)

Target: IL-10 (IL10) (Interleukin 10 (IL10))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IL-10 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: IL10-8711

Produktdetails anti-IL-10 Antikörper

Verwendungszweck: Interleukin 10 (IL10) (Immuno-regulation Marker) Antibody

Spezifität: Interleukin 10 (IL10) is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immuno-regulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II antigens, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immuno-regulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.

Aufreinigung: 200ug/ml of Ab purified by Protein A.

Immunogen: Recombinant full-length human Interleukin 10 (IL10) protein

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Details zu IL-10

Target: IL-10 (IL10) (Interleukin 10 (IL10))

Andere Bezeichnung: Interleukin 10

Hintergrund:

Cytokine Synthesis Inhibitory Factor (CSIF), GVHDS, IL-10, IL10, IL10A, Interleukin-10, T-cell Growth Inhibitory Factor (TGIF)

Human adrenal or lymph node tissues (IHC).

Molekulargewicht: 20kDa (Monomer), 37kDa (Dimer)

Gen-ID: 3586, 193717

UniProt: P22301

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints