Rekombinanter Inhibin alpha Antikörper (AA 233-362)

Produktnummer ABIN7863030

Der Maus Monoklonal anti-Inhibin alpha Antikörper wird verwendet zum Nachweis von Inhibin alpha in Proben von Human. Er wurde validiert für IHC.

Kurzübersicht für Rekombinanter Inhibin alpha Antikörper (AA 233-362) (ABIN7863030)

Target: Inhibin alpha (INHA) (Inhibin, alpha (INHA))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Inhibin alpha Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: RINHA-6919

Produktdetails anti-Inhibin alpha Antikörper

Bindungsspezifität: AA 233-362

Expressionssystem: HEK-293 Cells

Verwendungszweck: Recombinant Inhibin, alpha (INHA) (Gonadal Cell Marker) Antibody

Spezifität: It recognizes a 47 kDa protein, which is identified as alpha sub-unit of Inhibin. It is a gonadal protein that preferentially suppresses the secretion of pituitary follicle-stimulating hormone (FSH). Inhibin comprises two subunits, Inhibin A and Inhibin B. Each subunit consists of the same °™ subunit, covalently linked to 1 of 2 distinct subunits, æ-°™ or æ- æ. Originally isolated from ovarian follicular fluid and characterized as a disulphide-linked dimeric glycoprotein, inhibin belongs to the transforming growth factor æ (TFG æ) superfamily. Antibodies against Inhibin are useful in making a differentiation between adrenal cortical tumors and renal cell carcinoma. Sex cord stromal tumors of the ovary as well as trophoblastic tumors also demonstrate cytoplasmic positivity. Inhibin antibody is also used to make the differential diagnosis of intra-uterine vs. ectopic pregnancy in endometrial curetting.

Aufreinigung: 200ug/ml of Ab produced in HEK293 cell mammalian-based expression system.

Immunogen: Recombinant fragment of human Inhibin alpha protein (around aa 233-362) (exact sequence is proprietary)

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu Inhibin alpha

Target: Inhibin alpha (INHA) (Inhibin, alpha (INHA))

Andere Bezeichnung: Inhibin, alpha

Hintergrund:

A inhibin subunit, IHA, inhA, Inhibin alpha chain, Inhibin alpha subunit

Human prostate or testis.

Molekulargewicht: 47kDa

Gen-ID: 3623, 407506

UniProt: P05111

Pathways: Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion