Rekombinanter CD27 Antikörper

Produktnummer ABIN7857759

Der Maus Monoklonal anti-CD27 Antikörper wird verwendet zum Nachweis von CD27 in Proben von Human. Er wurde validiert für FACS, WB und IHC.

Kurzübersicht für Rekombinanter CD27 Antikörper (ABIN7857759)

Target: CD27 (CD27 Molecule (CD27))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD27 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC)

Klon: R137B4

Produktdetails anti-CD27 Antikörper

Expressionssystem: CHO Cells

Verwendungszweck: Recombinant CD27 (Tumor Necrosis Factor Receptor Superfamily 7) Antibody

Spezifität: CD27 (also known as S152 or T14) is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell costimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NFB and SAPK/JNK and induces apoptosis.

Aufreinigung: 200ug/ml of Ab produced in CHO cell mammalian-based expression system.

Immunogen: Recombinant human CD27 protein

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Details zu CD27

Target: CD27 (CD27 Molecule (CD27))

Andere Bezeichnung: CD27

Hintergrund:

LPFS2, S152, T cell activation antigen S152, T-cell activation antigen CD27, T14, TNFRSF7, TNFSF7, Tp55, Tumor necrosis factor receptor superfamily member 7

Ramos cells. Human peripheral blood lymphocytes. Human tonsil and stomach tissues. Human Spleen.

Molekulargewicht: 55kDa

Gen-ID: 939, 355307

UniProt: P26842

Pathways: Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints