Rekombinanter Cathepsin G Antikörper (N-Term)
Kurzübersicht für Rekombinanter Cathepsin G Antikörper (N-Term) (ABIN7857710)
Target
Alle Cathepsin G (CTSG) Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- N-Term
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Expressionssystem
- CHO Cells
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Verwendungszweck
- Recombinant Cathepsin G (Neutrophil Marker) Antibody
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Spezifität
- Cathepsins are members of the papain family of cysteine proteases which are involved in a variety of physiological processes such as proenzyme activation, enzyme inactivation, antigen presentation, hormone maturation, tissue remodeling and bone matrix resorption. Cathepsin G is a 29 kD serine protease and is located in neutrophilic polymorphonuclear leukocytes which contain specialized azurophil granules together with two other serine proteases, elastase and protease 3. These three proteases may participate in the killing and digestion of engulfed pathogens and in connective tissue remodeling at sites of inflammation. Cathepsin G has also been found to be essential for the induction of human natural killer cell cytotoxicity.
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Aufreinigung
- 200ug/ml of Ab produced in CHO cell mammalian-based expression system.
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Immunogen
- Prokaryotic recombinant protein corresponding to a 124 amino acid N-terminal region of the cathepsin G molecule
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Isotyp
- IgG1, kappa
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS
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Konservierungsmittel
- Azide free
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Haltbarkeit
- 24 months
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- Cathepsin G (CTSG)
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Andere Bezeichnung
- Cathepsin G
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Hintergrund
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CATG
THP-1 cells. Human bone marrow or lymphoid tissue.
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Molekulargewicht
- 32kDa
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Gen-ID
- 1511
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UniProt
- P08311
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Pathways
- ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones
Target
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