Rekombinanter SPARC Antikörper (C-Term)

Produktnummer ABIN7857698

Dieser Maus Monoklonal Antikörper detektiert spezifisch SPARC in WB und IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Rekombinanter SPARC Antikörper (C-Term) (ABIN7857698)

Target: SPARC (Secreted Protein, Acidic, Cysteine-Rich (Osteonectin) (SPARC))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SPARC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Klon: R15G12

Produktdetails anti-SPARC Antikörper

Bindungsspezifität: C-Term

Expressionssystem: CHO Cells

Verwendungszweck: Recombinant SPARC / Osteonectin / O-Nectin Antibody

Spezifität: Osteonectin (ON), also known as BM-40 or SPARC (secreted protein, acidic and rich in cysteine) is a multifunctional glycoprotein (32.5 kD) involved with tissue mineralization as well as extracellular matrix modelling. It is the most abundant glycoprotein secreted by human osteoblasts in developing bone and odontoblasts of developing teeth. ON mRNA and protein have been detected in non-mineralized tissues such as steroid-producing cells of the adrenal glands, suprabasal layers of the epidermis, glomeruli in the kidney, bronchi of the lung, megakaryocytes and large vessels. This organ-specific distribution in non-mineralized tissues suggests a role during human development.

Aufreinigung: 200ug/ml of Ab produced in CHO cell mammalian-based expression system.

Immunogen: Prokaryotic recombinant protein corresponding to a portion of the C-terminus of the human osteonectin molecule

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide store at 2 to 8 °C. Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu SPARC

Target: SPARC (Secreted Protein, Acidic, Cysteine-Rich (Osteonectin) (SPARC))

Andere Bezeichnung: SPARC

Hintergrund:

Basement membrane protein 40, BM40, Cysteine rich protein, OI17, ON, Osteonectin, Secreted acidic cystein rich glycoprotein, Secreted protein acidic and cysteine rich, Secreted protein acidic and rich in cysteine (SPARC)

Human placenta, lymph node or spleen. JEG3, A-375 or A549 cell lysates.

Molekulargewicht: 38kDa

Gen-ID: 6678, 111779, 708558

UniProt: P09486

Pathways: Autophagie