Rekombinanter Ret Proto-Oncogene Antikörper (C-Term)

Produktnummer ABIN7865342

Der Maus Monoklonal anti-Ret Proto-Oncogene Antikörper wird verwendet zum Nachweis von Ret Proto-Oncogene in Proben von Human. Er wurde validiert für IHC.

Kurzübersicht für Rekombinanter Ret Proto-Oncogene Antikörper (C-Term) (ABIN7865342)

Target: Ret Proto-Oncogene (RET)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Ret Proto-Oncogene Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: R3F8

Produktdetails anti-Ret Proto-Oncogene Antikörper

Bindungsspezifität: C-Term

Expressionssystem: CHO Cells

Verwendungszweck: Recombinant RET Proto-oncogene (Medullary Thyroid Carcinoma Marker) Antibody

Spezifität: The ret-proto-oncogene encodes a cell surface glycoprotein belonging to the tyrosine-kinase receptor family. Three main splice variants have been identified. Immunoreactivity of the ret-proto-oncogene in normal tissue has been found in Schwann cells, sympathetic ganglion, adrenal medulla, astrocytes and cortical neurons.

Aufreinigung: 200ug/ml of Ab produced in CHO cell mammalian-based expression system.

Immunogen: Prokaryotic recombinant fusion protein corresponding to the extreme C-terminal cytoplasmic region of the human ret oncoprotein

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Details zu Ret Proto-Oncogene

Target: Ret Proto-Oncogene (RET)

Andere Bezeichnung: RET Proto-oncogene

Hintergrund:

Cadherin family member 12 (CDHF12), Cadherin related family member 16 (CDHR16), ELKS, HSCR1, Hydroxyaryl protein kinase, MEN2A, MEN2B, MTC1, Multiple endocrine neoplasia and medullary thyroid carcinoma 1, Oncogene RET, Proto-oncogene c-Ret, Proto-oncogene tyrosine-protein kinase receptor ret, PTC, RET, RET ELE1, RET51, RET9

Human brain, breast, colon or prostate carcinoma.

Molekulargewicht: 150kDa (precursor), 170kDa (Mature)

Gen-ID: 5979, 350321

UniProt: P07949

Pathways: RTK Signalweg, Dopaminergic Neurogenesis, Regulation of Cell Size, Tube Formation