Rekombinanter HSPH1 Antikörper (C-Term)
Kurzübersicht für Rekombinanter HSPH1 Antikörper (C-Term) (ABIN7857690)
Target
Alle HSPH1 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- C-Term
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Expressionssystem
- CHO Cells
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Verwendungszweck
- Recombinant Heat Shock Protein 105 kDa / HSP105 (Basaloid Skin Tumor Marker) Antibody
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Spezifität
- Heat shock protein (HSP) 105 exists as two isoforms, alpha and beta which belong to the HSP105/HSP110 protein family. HSP105 acts as both a chaperone to prevent thermal aggregation of proteins and as a regulator of mammalian cells. The HSP105 isoforms are found in the cytoplasm but not in the nucleoli under non-stressed and stressed conditions. In rodents, HSP105 isoforms are moderately expressed in the adrenal glands, spleen, liver and heart and both are markedly increased after heat shock. In the testis, HSP105 is specifically localized in the cytoplasm of germ cells and may translocate to the nucleus after heat shock. The most abundant expression occurs in the brain with nuclear and cytoplasmic expression in nearly all neurones, oligodendrocytes, microglia and astrocytes. Increased expression during embryogenesis suggests that HSP105 may have an important role during mouse embryo development.
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Aufreinigung
- 200ug/ml of Ab produced in CHO cell mammalian-based expression system.
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Immunogen
- Prokaryotic recombinant protein of 31 kD corresponding to the C-terminus of the heat shock protein 105 molecule
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Isotyp
- IgG1, kappa
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS
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Konservierungsmittel
- Azide free
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- HSPH1 (Heat Shock 105kDa/110kDa Protein 1 (HSPH1))
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Andere Bezeichnung
- Heat Shock Protein 105 kDa
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Hintergrund
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HSP105, HSP110, KIAA0201, HSPH1, Heat shock protein 105 kDa, Antigen NY-CO-25, Heat shock 110 kDa protein, Heat shock protein family H member 1
Human brain or testis.
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Molekulargewicht
- 105kDa
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Gen-ID
- 10808
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UniProt
- Q92598
Target
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