DDB1 Antikörper (AA 951-1140)

Produktnummer ABIN742455

Dieses Anti-DDB1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von DDB1 in ELISA, IHC (p), IHC (fro), IF (cc) und IF (p). Geeignet für Human.

Kurzübersicht für DDB1 Antikörper (AA 951-1140) (ABIN742455)

Target: DDB1 (Damage Specific DNA Binding Protein 1 (DDB1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DDB1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-DDB1 Antikörper

Bindungsspezifität: AA 951-1140

Homologie: Human,Mouse,Rat,Cow,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DDB1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu DDB1

Target: DDB1 (Damage Specific DNA Binding Protein 1 (DDB1))

Andere Bezeichnung: DDB1

Hintergrund:

Synonyms: DNA damage-binding protein 1, DDB1, DDB-1, ,Damage specic DNA binding protein 1, DDB 1, DDB p127 subunit, DDBa, DNA damage binding protein 1, UV damaged DNA binding factor, UV damaged DNA binding protein 1, UV DDB 1, UV-DDB1, X associated protein 1, XAP 1, XAP1, Xeroderma pigmentosum group E complementing protein, XPCE, XPE, XPE binding factor, XPE-BF.

Background: This gene encodes the large subunit of DNA damage-binding protein which is a heterodimer composed of a large and a small subunit. This protein functions in nucleotide-excision repair. Its defective activity causes the repair defect in the patients with xeroderma pigmentosum complementation group E (XPE). However, it remains for mutation analysis to demonstrate whether the defect in XPE patients is in this gene or the gene encoding the small subunit. In addition, Best vitelliform mascular dystrophy is mapped to the same region as this gene on 11q, but no sequence alternations of this gene are demonstrated in Best disease patients. [provided by RefSeq].

Gen-ID: 1642

Pathways: DNA Reparatur