Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

ICOS Antikörper (PE-Cy5)

Dieses Anti-ICOS-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ICOS in WB. Geeignet für Human, Maus, Ratte und Schwein.
Produktnummer ABIN742392

Kurzübersicht für ICOS Antikörper (PE-Cy5) (ABIN742392)

Target

Alle ICOS Antikörper anzeigen
ICOS (Inducible T-Cell Co-Stimulator (ICOS))

Reaktivität

Human, Maus, Ratte, Schwein

Wirt

  • 84
  • 19
  • 13
  • 6
  • 1
  • 1
  • 1
  • 1
Kaninchen

Klonalität

  • 80
  • 45
  • 1
Polyklonal

Konjugat

  • 54
  • 18
  • 9
  • 9
  • 5
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser ICOS Antikörper ist konjugiert mit PE-Cy5

Applikation

  • 72
  • 43
  • 43
  • 32
  • 19
  • 16
  • 14
  • 13
  • 9
  • 8
  • 7
  • 6
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Spezifität

    This antibody may also have a secondary cross-reactivity with AP-1 complex-associated regulatory protein due to a 77 % non-contiguous sequence similarity in the corresponding immunogen region.

    Kreuzreaktivität

    Human

    Homologie

    Mouse,Rat,Pig

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human ICOS

    Isotyp

    IgG
  • Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    ICOS (Inducible T-Cell Co-Stimulator (ICOS))

    Andere Bezeichnung

    ICOS/CD278

    Hintergrund

    Synonyms: AILIM, CD278, CVID1, Inducible T-cell costimulator, Activation-inducible lymphocyte immunomediatory molecule, ICOS

    Background: Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes (By similarity).

    Molekulargewicht

    23kDa

    Gen-ID

    29851

    UniProt

    Q9Y6W8

    Pathways

    Cancer Immune Checkpoints
Sie sind hier:
Chat with us!