D-Dimer Antikörper

Produktnummer ABIN7849757

Der Maus Monoklonal anti-D-Dimer Antikörper (Klon D10) (ABIN7849757) detektiert spezifisch D-Dimer in ELISA, WB und LF. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für D-Dimer Antikörper (ABIN7849757)

Target: D-Dimer

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser D-Dimer Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Lateral Flow (LF)

Klon: D10

Produktdetails anti-D-Dimer Antikörper

Verwendungszweck: Monoclonal Anti-D-dimer (Detection Ab)

Spezifität: It specifically recognize human D-dimer antigen, and does not cross react with BSA, but has week cross-reactivity withfibrinogen.

Produktmerkmale: This antibody may be used as in antibody pair experiments such as ELISA.

Aufreinigung: Protein A or G purified

Reinheit: >95 % by HPLC & SDS-PAGE

Immunogen: Human D-dimer protein.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.01 M PBS ( pH 7.4) without preservative.

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freeze and thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and store at -20°C for long term (at least one year). Avoid repeated freeze and thaw cycles.

Haltbarkeit: 12 months

Details zu D-Dimer

Target: D-Dimer

Hintergrund: D-dimer is a fibrin degradation product (or FDP), a small protein fragment present in the blood after a blood clot is degraded by fibrinolysis. It is so named because it contains two crosslinked D fragments of the fibrin protein. The D-dimer antigen is a unique marker of fibrin degradation that is formed by the sequential action of 3 enzymes: thrombin, factor XIIIa, and plasmin. Its concentration may be determined by a blood test to help diagnose thrombosis. Since its introduction in the 1990s, it has become an important test performed in patients suspected of thrombotic disorders. While a negative result practically rules out thrombosis, a positive result can indicate thrombosis but does not rule out other potential causes. Its main use, therefore, is to exclude thromboembolic disease where the probability is low. In addition, it is used in the diagnosis of the blood disorder disseminated intravascular coagulation.