Rekombinanter D-Dimer Antikörper

Produktnummer ABIN7861194

Der Kaninchen Monoklonal anti-D-Dimer Antikörper wird verwendet zum Nachweis von D-Dimer in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für Rekombinanter D-Dimer Antikörper (ABIN7861194)

Target: D-Dimer

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser D-Dimer Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: FGG-13043R

Produktdetails anti-D-Dimer Antikörper

Verwendungszweck: Recombinant D-Dimer / Fibrinogen gamma chain Antibody

Spezifität: The plasma glycoprotein Fibrinogen is synthesized in the liver and comprises three structurally different subunits: a, b and g. Fibrinogen is important in platelet aggregation, the final step of the coagulation cascade (i.e. the formation of Fibrin) and determination of plasma viscosity and erythrocyte aggregation. It is both constitutively expressed and inducible during an acute phase reaction. Hemostasis following tissue injury deploys essential plasma procoagulants (Prothrombin and Factors X, IX, V and VIII), which are involved in a blood coagulation cascade leading to the formation of insoluble Fibrin clots and the promotion of platelet aggregation. Following vascular injury, Fibrinogen is cleaved by Thrombin to form Fibrin, which is the most abundant component of blood clots. The cleavage products of Fibrinogen regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities and are mitogens for several cell types. This antibody is directed against a neoantigenic determinant expressed on the human fragment D-dimer. D-dimer is a protein fragment (small piece) that's made when a blood clot dissolves in your body. At D-dimer test is done to determine if a person has any blood clotting disorder.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant human FGA protein (exact sequence is proprietary)

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Details zu D-Dimer

Target: D-Dimer

Hintergrund:

fibrinogen, gamma polypeptide testicular tissue protein Li 70

HepG2 or A-549 cells. Human kidney.

Molekulargewicht: 57kDa

Gen-ID: 2266

UniProt: P02679