Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
0.9 % NaCl without preservative.
Konservierungsmittel
Without preservative
Handhabung
Avoid repeated freeze and thaw cycles.
Lagerung
4 °C
Informationen zur Lagerung
Aliquot and store at 2-8°C for long term (at least one year). Avoid repeated freeze and thaw cycles.
Haltbarkeit
12 months
Target
AMH
(Anti-Mullerian Hormone (AMH))
Andere Bezeichnung
Muellerian-inhibiting factor
Hintergrund
Anti-Müllerian hormone (AMH), also known as Müllerian-inhibiting hormone (MIH), is a glycoprotein hormone structurally related to inhibin and activin from the transforming growth factor beta superfamily, whose key roles are in growth differentiation and folliculogenesis. In humans, it is encoded by the AMH gene, on chromosome 19p13.3, while its receptor is encoded by the AMHR2 gene on chromosome 12.AMH is activated by SOX9 in the Sertoli cells of the male fetus. Its expression inhibits the development of the female reproductive tract, or Müllerian ducts (paramesonephric ducts), in the male embryo, thereby arresting the development of fallopian tubes, uterus, and upper vagina.