H2AFX Antikörper
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- Target Alle H2AFX Antikörper anzeigen
- H2AFX (H2A Histone Family, Member X (H2AFX))
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Hund, Schwein
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser H2AFX Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Rind (Kuh), Hund, Human, Maus, Schwein, Ratte
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Histone H2A
- Isotyp
- IgG
- Top Product
- Discover our top product H2AFX Primärantikörper
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- Applikationshinweise
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WB(1:100-500)
Optimal working dilution should be determined by the investigator. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C for 12 months.
- Haltbarkeit
- 12 months
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- Target
- H2AFX (H2A Histone Family, Member X (H2AFX))
- Andere Bezeichnung
- Histone H2A.x (H2AFX Produkte)
- Hintergrund
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Synonyms: H2A histone family member X, Histone H2A.x, H2afx, H2a.x, H2ax, Hist5-2ax, H2A.X, H2A/X, H2AX, H2AFX, H2AX_HUMAN.
Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Jul 2008].
- Molekulargewicht
- 16kDa
- Gen-ID
- 3014
- Pathways
- Telomere Maintenance, DNA Reparatur, Positive Regulation of Response to DNA Damage Stimulus
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