Aquaporin 7 Antikörper (AA 251-342) (Cy5.5)

Produktnummer ABIN741260

Der Kaninchen Polyklonal Anti-Aquaporin 7-Antikörper wurde für FACS, IF (cc) und IF (p) validiert. Er ist geeignet, Aquaporin 7 in Proben von Human, Ratte und Maus zu detektieren.

Kurzübersicht für Aquaporin 7 Antikörper (AA 251-342) (Cy5.5) (ABIN741260)

Target: Aquaporin 7 (AQP7)

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Aquaporin 7 Antikörper ist konjugiert mit Cy5.5

Applikation: Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-Aquaporin 7 Antikörper (Cy5.5)

Bindungsspezifität: AA 251-342

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Pig,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human AQP7

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Aquaporin 7

Target: Aquaporin 7 (AQP7)

Andere Bezeichnung: Aqp7

Hintergrund:

Synonyms: AQP9, AQP7L, AQPap, GLYCQTL, Aquaporin-7, AQP-7, Aquaglyceroporin-7, Aquaporin adipose, Aquaporin-7-like, AQP7

Background: Water is a critical component of all living cells. Interestingly, tissue membranes show a great degree of water permeability. Mammalian red cells, renal proximal tubules, and descending thin limb of Henle are extraordinarily permeable to water. Water crosses hydrophobic plasma membranes either by simple diffusion or through a facilitative transport mechanism mediated by special protein "aquaporin". Over the last decade, genes for several members of aquaporin family have been cloned, expressed, and their distribution studied in many tissues. AQP0 or MIP26 (major intrinsic protein 26kD), and Aquaporin 1 (AQP1, purified from red cells) also called CHIP28 (channel forming integral protein, 28kD, 268aa, gene locus 7p14) has been the foundation of the growing family of aquaporin. The lens specific AQP0 represents up to 80 % of total lens membrane protein. Defects in MIP26 are cause of autosomal dominant cataract. The cataract Fraser mutation (CATFR or Shriveled) is a transposon induced splicing error that substitutes a long terminal repeat sequence for the C terminus of MIP. The lens opacity mutation (LOP) is an amino acid substitution that inhibits targeting of MIP to the cell membrane.

Gen-ID: 364

UniProt: O14520