RPA1 Antikörper

Produktnummer ABIN7833814

Der Kaninchen Polyklonal anti-RPA1 Antikörper wird verwendet zum Nachweis von RPA1 in Proben von Saccharomyces cerevisiae. Er wurde validiert für WB und IP.

Kurzübersicht für RPA1 Antikörper (ABIN7833814)

Target: RPA1 (Replication Protein A1, 70kDa (RPA1))

Reaktivität: Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RPA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Produktdetails anti-RPA1 Antikörper

Verwendungszweck: Anti-RFa1/Rpa1 | Replication factor protein 1 (Saccharomyces cerevisiae)

Kreuzreaktivität (Details): Saccharomyces cerevisiae

Immunogen: Purified

Anwendungsinformationen

Applikationshinweise: 1: 200 (IP), 1 : 2000 (WB)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Serum. Contains 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C, make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.

Details zu RPA1

Target: RPA1 (Replication Protein A1, 70kDa (RPA1))

Andere Bezeichnung: RFa1/Rpa1

Hintergrund: Rfa1 (Replication Factor A protein 1) as part of the replication protein A (RPA/RP-A), a single-stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. Binds to single-stranded sequences participating in DNA replication in addition to those mediating transcriptional repression (URS1) and activation (CAR1). Stimulates the activity of a cognate strand exchange protein (SEP1). It cooperates with T-AG and DNA topoisomerase I to unwind template DNA containing the simian virus 40 origin of DNA replication.

Molekulargewicht: 70.3 kDa

Gen-ID: 851266

UniProt: P22336

Pathways: Telomere Maintenance, DNA Reparatur, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA