CCL19 Antikörper (AA 26-108)

Produktnummer ABIN740505

Dieses Anti-CCL19-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CCL19 in WB, ELISA, IF (cc), IF (p), IHC (p) und IHC (fro). Geeignet für Human und Ratte. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für CCL19 Antikörper (AA 26-108) (ABIN740505)

Target: CCL19 (Chemokine (C-C Motif) Ligand 19 (CCL19))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCL19 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-CCL19 Antikörper

Bindungsspezifität: AA 26-108

Kreuzreaktivität: Human, Ratte

Homologie: Mouse,Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse CCL19

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-CCL19 Antikörper (ABIN740505)

Borrelli, Abrão, Taube, Darb-Esfahani, Köhler, Kaufmann, Chiantera, Mechsner: "Immunohistochemical Investigation of Metastasis-Related Chemokines in Deep-Infiltrating Endometriosis and Compromised Pelvic Sentinel Lymph Nodes." in: Reproductive sciences (Thousand Oaks, Calif.), (2015) (PubMed).

Details zu CCL19

Target: CCL19 (Chemokine (C-C Motif) Ligand 19 (CCL19))

Andere Bezeichnung: CCL19/MIP-3 beta

Hintergrund:

Synonyms: ELC, CKb11, MIP3B, Scya19, exodus-3, C-C motif chemokine 19, Epstein-Barr virus-induced molecule 1 ligand chemokine, EBI1 ligand chemokine, Small-inducible cytokine A19, Ccl19

Background: Strongly chemotactic for naive (L-selectinhi) CD4 T-cells and for CD8 T-cells and weakly attractive for resting B-cells and memory (L-selectinlo) CD4 T-cells. May play a role in promoting encounters between recirculating T-cells and dendritic cells and in the migration of activated B-cells into the T-zone of secondary lymphoid tissues. Binds to chemokine receptor CCR7. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.

Gen-ID: 24047

UniProt: O70460

Pathways: Positive Regulation of Immune Effector Process