CCL19 Antikörper (N-Term)

Produktnummer ABIN6260539

Produktdetails anti-CCL19 Antikörper

Target: CCL19 (Chemokine (C-C Motif) Ligand 19 (CCL19))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCL19 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: CCL19 Antibody detects endogenous levels of total CCL19.

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CCL19, corresponding to a region within N-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu CCL19

Target: CCL19 (Chemokine (C-C Motif) Ligand 19 (CCL19))

Andere Bezeichnung: CCL19 (CCL19 Produkte)

Synonyme: CKb11 antikoerper, ELC antikoerper, MIP-3b antikoerper, MIP3B antikoerper, SCYA19 antikoerper, CCL19 antikoerper, Scya19 antikoerper, exodus-3 antikoerper, C-C motif chemokine ligand 19 antikoerper, chemokine (C-C motif) ligand 19 antikoerper, CCL19 antikoerper, ccl19 antikoerper, Ccl19 antikoerper

Hintergrund:

Description: May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.

Gene: CCL19

Molekulargewicht: 11kDa

Gen-ID: 6363

UniProt: Q99731

Pathways: Positive Regulation of Immune Effector Process