MYOD1 Antikörper (AA 51-150)

Produktnummer ABIN740340

Dieses Anti-MYOD1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von MYOD1 in WB, ELISA, FACS, IHC (p) und IHC (fro). Geeignet für Human, Maus und Ratte. Dieses Primary Antibody wurde in 3+ Publikationen zitiert.

Kurzübersicht für MYOD1 Antikörper (AA 51-150) (ABIN740340)

Target: MYOD1 (Myogenic Differentiation 1 (MYOD1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MYOD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-MYOD1 Antikörper

Bindungsspezifität: AA 51-150

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse MyoD1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-MYOD1 Antikörper (ABIN740340)

Dai, Zhang, Wang, Liu, Li, Ding, Guo: "MicroRNA-128 regulates the proliferation and differentiation of bovine skeletal muscle satellite cells by repressing Sp1." in: Molecular and cellular biochemistry, Vol. 414, Issue 1-2, pp. 37-46, (2016) (PubMed).

Sente, Van Berendoncks, Jonckheere, Rodenburg, Lauwers, Van Hoof, Wouters, Lardon, Hoymans, Vrints: "Primary skeletal muscle myoblasts from chronic heart failure patients exhibit loss of anti-inflammatory and proliferative activity." in: BMC cardiovascular disorders, Vol. 16, pp. 107, (2016) (PubMed).

Gong, Zhao, Yang, Li, Chen, Chen, Zhou: "The control of mesenchymal stem cell differentiation using dynamically tunable surface microgrooves." in: Advanced healthcare materials, Vol. 3, Issue 10, pp. 1608-19, (2014) (PubMed).

Details zu MYOD1

Target: MYOD1 (Myogenic Differentiation 1 (MYOD1))

Andere Bezeichnung: MyoD1

Hintergrund:

Synonyms: MYF3, MyoD, Myod-1, bHLHc1, AI53393, Myoblast determination protein 1, Myod1

Background: Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYF5 and MYOG, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins.

Gen-ID: 17927

UniProt: P10085

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development