CD51 Antikörper

Produktnummer ABIN7828788

Der Ratte Monoklonal anti-CD51 Antikörper (Klon RMV-7) (ABIN7828788) detektiert spezifisch CD51 in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Maus.

Kurzübersicht für CD51 Antikörper (ABIN7828788)

Target: CD51 (ITGAV) (Integrin alpha V (ITGAV))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser CD51 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: RMV-7

Produktdetails anti-CD51 Antikörper

Verwendungszweck: Purified Anti-Mouse CD51 Antibody[RMV-7]

Aufreinigung: >98%, Protein A/G purified

Reinheit: >98 %

Immunogen: Recombinant MouseCD51 protein

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: FCM 2 μg/mL(0.5x106-1x106 cells)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: ≥ 1 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.05 % non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu CD51

Target: CD51 (ITGAV) (Integrin alpha V (ITGAV))

Andere Bezeichnung: CD51

Hintergrund: Integrin alpha-V;Integrin αV chain;Vitronectin Receptor;αV integrin;Itgav;vitronectin R;integrin &alpha-V-V,CD51 is a 140 kD protein, also known as αV integrin, vitronectin receptor, and integrin αV. It is a member of the integrin family, expressed on activated T cells, polymorphonuclear granulocytes, platelets, blastocysts, and osteoclasts. CD51 forms heterodimers by association with integrins β1, β3, β5 or β6; these complexes then act as receptors for multiple extracellular matrix proteins (ECM). The αv integrin heterodimers have varied functions in development, stimulation/activation and homeostasis. The primary ligands for CD51 complexes are fibronectin, fibrinogen, vitronectin, thrombspondin, von Willebrand factor, and CD31. The RMV-7 antibody has been reported to block binding of CD51 to vitronectin, fibronectin, and CD31 in some cell types, as well as blocking LAK cell cytotoxicity. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

UniProt: P43406

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex