Rekombinanter SGK1 Antikörper

Produktnummer ABIN7828557

Der Kaninchen Monoklonal anti-SGK1 Antikörper (Klon A670) (ABIN7828557) detektiert spezifisch SGK1 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Rekombinanter SGK1 Antikörper (ABIN7828557)

Target: SGK1 (serum/glucocorticoid Regulated Kinase 1 (SGK1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser SGK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: A670

Produktdetails anti-SGK1 Antikörper

Verwendungszweck: Recombinant SGK1 Monoclonal Antibody

Aufreinigung: Protein A purified

Immunogen: Recombinant human SGK1 fragment

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: WB 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu SGK1

Target: SGK1 (serum/glucocorticoid Regulated Kinase 1 (SGK1))

Andere Bezeichnung: SGK1

Hintergrund: SGK1,SGK,OTTHUMP00000017247,Serine/threonine protein kinase SGK,Serine/threonine protein kinase Sgk1,Serine/threonine-protein kinase Sgk1,Serum and glucocorticoid regulated kinase,Serum/glucocorticoid regulated kinase,Serum/glucocorticoid regulated kinase 1,Serum/glucocorticoid-regulated kinase 1,SGK 1,Sgk1 variant i3,Serum and glucocorticoid-inducible kinase (SGK) is a serine/threonine kinase closely related to Akt. SGK is rapidly induced in response to a variety of stimuli, including serum, glucocorticoid, follicle stimulating hormone, osmotic shock, and mineralocorticoids. SGK activation can be accomplished via HGF PI3K-dependent pathways and by integrin-mediated PI3K-independent pathways. Induction and activation of SGK has been implicated in activating the modulation of anti-apoptotic and cell cycle regulation. SGK also plays an important role in activating certain potassium, sodium, and chloride channels, suggesting its involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. SGK is negatively regulated by ubiquitination and proteasome degradation.In addition to its membrane channel and carrier functions, SGK1 also regulates a broad range of targets, such as GSK-3, NEDD4, iNOS, AMPAR, PSD95, Tau, NF-κB, CREB, and FKHR-L1. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molekulargewicht:

Calculated MW: 49 kDa

Observed MW: 45-55 kDa The actual band is not consistent with the expectation.

UniProt: O00141

Pathways: MAPK Signalweg, Notch Signalweg, Steroid Hormone Mediated Signaling Pathway