Rekombinanter ALIX Antikörper

Produktnummer ABIN7828485

Der Kaninchen Monoklonal anti-ALIX Antikörper (Klon A493) (ABIN7828485) detektiert spezifisch ALIX in WB, IHC und IP. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für Rekombinanter ALIX Antikörper (ABIN7828485)

Target: ALIX (PDCD6IP) (Programmed Cell Death 6 Interacting Protein (PDCD6IP))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser ALIX Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Klon: A493

Produktdetails anti-ALIX Antikörper

Verwendungszweck: Recombinant ALIX Monoclonal Antibody

Aufreinigung: Protein A purified

Immunogen: Recombinant human ALIX fragment

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: WB 1:2000-1:10000,IHC 1:100-1:500,IP 1:25-1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu ALIX

Target: ALIX (PDCD6IP) (Programmed Cell Death 6 Interacting Protein (PDCD6IP))

Andere Bezeichnung: ALIX

Hintergrund: AIP,DRIP,KIAA,PDCD6IP,AIP1,ALIX,DRIP4,HP95,KIAA1375,Programmed cell death 6-interacting protein (PDCD6IP), plays an important role in the endosomal sorting complexes required for transport (ESCRT) pathway in the abscission stage of cytokinesis and apoptosis. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the protein binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. It also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this protein and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molekulargewicht:

Calculated MW: 96 kDa

Observed MW: 90/100 kDa The actual band is not consistent with the expectation.

UniProt: Q8WUM4

Pathways: p53 Signalweg, EGFR Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Tube Formation