Rekombinanter KDM2A Antikörper

Produktnummer ABIN7828363

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch KDM2A in WB, IHC und IF. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für Rekombinanter KDM2A Antikörper (ABIN7828363)

Target: KDM2A (Lysine (K)-Specific Demethylase 2A (KDM2A))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser KDM2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Klon: A401

Produktdetails anti-KDM2A Antikörper

Verwendungszweck: Recombinant KDM2A Monoclonal Antibody

Aufreinigung: Protein A purified

Immunogen: Recombinant human KDM2A fragment

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: WB 1:1000-1:5000,IHC 1:50-1:100,IF 1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu KDM2A

Target: KDM2A (Lysine (K)-Specific Demethylase 2A (KDM2A))

Andere Bezeichnung: KDM2A

Hintergrund: CXXC,FBXL,KIAA,FBL,KDM2A,CXXC8,FBL11,FBL7,FBXL11,JHDM1A,LILINA,lysine demethylase 2A,KIAA1004,CXXC8,FBL11,FBL7,FBXL11,JHDM1A,LILINA,lysine demethylase 2A,[Histone-H3]-lysine-36 demethylase 1A,CXXC-type zinc finger protein 8,F box / LRR repeat protein 11,F box and leucine rich repeat protein 11,F box protein FBL7,F-box and leucine-rich repeat protein 11,F-box protein FBL7,F-box protein Lilina,F-box/LRR-repeat protein 11,JmjC domain-containing histone demethylation protein 1A,Jumonji C domain containing histone demethylase 1A,Lysine (K) specific demethylase 2A,Lysine-specific demethylase 2A,Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and Trimethylated H3 'Lys-36'. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at the centromere. Required to sustain centromeric integrity and genomic stability, particularly during mitosis. Regulates circadian gene expression by repressing the transcriptional activator activity of CLOCK-ARNTL/BMAL1 heterodimer and RORA in a catalytically-independent manner. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molekulargewicht:

Calculated MW: 133 kDa

Observed MW: 140 kDa The actual band is not consistent with the expectation.

UniProt: Q9Y2K7

Pathways: Warburg Effekt