Rekombinanter Histone H2A Antikörper (H2AK5ac)

Produktnummer ABIN7828262

Der Kaninchen Monoklonal anti-Histone H2A Antikörper wird verwendet zum Nachweis von Histone H2A in Proben von Human, Ratte und Maus. Er wurde validiert für WB und ChIP.

Kurzübersicht für Rekombinanter Histone H2A Antikörper (H2AK5ac) (ABIN7828262)

Target: Histone H2A

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Histone H2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)

Klon: A109

Produktdetails anti-Histone H2A Antikörper

Bindungsspezifität: H2AK5ac

Verwendungszweck: Recombinant Histone H2A (Acetyl Lys5) Monoclonal Antibody

Aufreinigung: Protein A purified

Immunogen: Acetylated human histone H2A (Lys5) peptide

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: WB 1:1000-1:2000,ChIP 6 μg/ 5x106 cells

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu Histone H2A

Target: Histone H2A

Hintergrund: H2AFM,HIST1H2AB,H2AFA,HIST1H2AE,H2AC4,H2AC8,Histone post-translational modifications (PTMs), known as the ""histone code"", are key mechanisms of epigenetics that modulate chromatin structures. The PTMs on histone including acetylation, methylation, phosphorylation, and novel acylations directly affect the accessibility of chromatin to transcription factors and other epigenetic regulators, altering genome stability and gene transcription. Histone acetylation, tightly controlled by the opposing action of histone acetyltransferases (HATs) and histone deacetylases (HDACs), occurs primarily at lysine residues on the N-terminal tails of histones H2A (Lys5, 9, and 15), H2B (Lys5, 12, 15, 16, and 20), H3 (Lys4, 9, 14, 18, 23, 27, and 36), and H4 (Lys5, 8, 12, 16, and 20), and plays vital roles in the regulation of gene expression, DNA damage repair, chromatin dynamics, etc. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molekulargewicht:

Calculated MW: 14 kDa

Observed MW: 14 kDa

UniProt: P04908