Histone H2A Antikörper (pThr121)

Produktnummer ABIN6256470

Produktdetails anti-Histone H2A Antikörper

Target: Histone H2A

Bindungsspezifität: pThr121

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Histone H2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Spezifität: Phospho-Histone H2A (Thr121) Antibody detects endogenous levels of Histone H2A only when phosphorylated at Threonine 121

Kreuzreaktivität: Human, Maus, Ratte (Rattus)

Aufreinigung: The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

Immunogen: A synthesized peptide derived from human Histone H2A around the phosphorylation site of Threonine 121

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:200 WB 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C.Stable for 12 months from date of receipt

Haltbarkeit: 12 months

Details zu Histone H2A

Target: Histone H2A

Abstract: Histone H2A Produkte

Synonyme: 5499 antikoerper, CG5499 antikoerper, Dmel\\CG5499 antikoerper, H2A antikoerper, H2A.F/Z antikoerper, H2A.X antikoerper, H2A.Z antikoerper, H2AV antikoerper, H2AV_DROM antikoerper, H2AX antikoerper, H2AZ antikoerper, H2Av antikoerper, H2AvD antikoerper, H2a.V antikoerper, H2av antikoerper, H2avD antikoerper, HIS antikoerper, HIS2AV antikoerper, HIS2AVD antikoerper, His antikoerper, His2 antikoerper, His2AV antikoerper, His2AvD antikoerper, HisH2Av antikoerper, Hist antikoerper, Hist2av antikoerper, gamma-H2Av antikoerper, gamma-HIS2AV antikoerper, gamma-His2Av antikoerper, gammaH2Av antikoerper, h2AvD antikoerper, his antikoerper, l(3)05146 antikoerper, l(3)810 antikoerper, l(3)97Dd antikoerper, l(3)L1602 antikoerper, DDBDRAFT_0205974 antikoerper, DDBDRAFT_0216271 antikoerper, DDB_0205974 antikoerper, DDB_0216271 antikoerper, RGD1564767 antikoerper, H2a-221 antikoerper, H2A-III antikoerper, HIST1H2AA antikoerper, Histone H2A variant antikoerper, putative histone H2A antikoerper, histone H2A antikoerper, histone cluster 1 H2A family member F antikoerper, histone H2A-like antikoerper, histone cluster 1, H2af antikoerper, histone2A1 antikoerper, histone cluster 1, H2A, III antikoerper, histone cluster 1, H2ac antikoerper, His2Av antikoerper, LMJF_17_0280 antikoerper, H2AX antikoerper, Hist1h2af antikoerper, LOC100425378 antikoerper, his2a1 antikoerper, HIST1H2A3 antikoerper, HIST1H2AC antikoerper, h2a-A antikoerper

Hintergrund:

Description: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Gene: HIST1H2AG, HIST1H2AI, HIST1H2AK, HIST1H2AL, HIST1H2AM

Molekulargewicht: 15kDa

Gen-ID: 83, 298, 330

UniProt: P0C0S8, P04908, P20671, Q96KK5, Q6FI13, Q7L7L0