Rekombinanter Glutamate Receptor 3 Antikörper
Kurzübersicht für Rekombinanter Glutamate Receptor 3 Antikörper (ABIN7828228)
Target
Alle Glutamate Receptor 3 (GRIA3) Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Recombinant Glutamate receptor 3 Monoclonal Antibody
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Aufreinigung
- Protein A purified
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Immunogen
- Recombinant human Glutamate receptor 3 fragment
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Isotyp
- IgG, kappa
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Applikationshinweise
- WB 1:1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 mg/mL
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Buffer
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Haltbarkeit
- 12 months
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- Glutamate Receptor 3 (GRIA3) (Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3))
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Andere Bezeichnung
- Glutamate receptor 3
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Hintergrund
- MRX,GRIA,GLUR,GluA,GLUR-K,GRIA3,GLUR-C,GLUR-K3,GLUR3,GLURC,GluA3,MRX94,AMPA 3,AMPA selective glutamate receptor 3,AMPA-selective glutamate receptor 3,dJ1171F9.1,GLUK3,GluR 3,GLUR C,GLUR K3,GluR-3,Glutamate ionotropic receptor AMPA type subunit 3,Glutamate receptor,Glutamate receptor 3,Glutamate receptor C,Glutamate receptor ionotrophic AMPA 3,Glutamate receptor ionotropic,Glutamate receptor subunit 3,GRIA 3,Ionotrophic Glutamate Receptor,ionotropic,AMPA receptors (AMPARs) are comprised of four subunits (GluR 1-4) that assemble as homo- or hetero-tetramers and mediate the majority of fast excitatory transmissions in the CNS. AMPARs are implicated in synapse formation, stabilization and plasticity. Glutamate receptor 3 (GluR3) knockout mice exhibited normal basal synaptic transmission and long-term depression (LTD) but enhanced long-term potentiation (LTP). In contrast, GluR 2/3 double knockout mice are impaired in basal synaptic transmission. Aberrant GluR3 expression or activity is implicated in a number of diseases, including autoimmune epilepsy, X-linked mental retardation, Rett's syndrome, amyotrophic lateral sclerosis and Alzheimer disease. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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Molekulargewicht
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Calculated MW: 101 kDa
Observed MW: 101 kDa
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UniProt
- P42263
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Pathways
- PI3K-Akt Signalweg, cAMP Metabolic Process, Synaptic Membrane
Target
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