Rekombinanter FOXL2 Antikörper

Produktnummer ABIN7828214

Der Kaninchen Monoklonal anti-FOXL2 Antikörper wird verwendet zum Nachweis von FOXL2 in Proben von Human, Maus und Ratte. Er wurde validiert für WB und IHC.

Kurzübersicht für Rekombinanter FOXL2 Antikörper (ABIN7828214)

Target: FOXL2 (Forkhead Box L2 (FOXL2))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser FOXL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Klon: A225

Produktdetails anti-FOXL2 Antikörper

Verwendungszweck: Recombinant FOXL2 Monoclonal Antibody

Aufreinigung: Protein A purified

Immunogen: Recombinant human FOXL2 fragment

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: WB 1:1000,IHC 1:100-1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu FOXL2

Target: FOXL2 (Forkhead Box L2 (FOXL2))

Andere Bezeichnung: FOXL2

Hintergrund: FOXL,Pfrk,Foxl2,Winged helix forkhead transcription factor 2 (FOXL2) promotes the proliferation and differentiation of granulosa cells by regulating the transcription of target genes, which is a key factor for ovarian differentiation and function maintenance. FOXL2 repels SOX9, Sertoli cells inhibit the transcription of SOX9 gene to prevent the transdifferentiation of the ovary to the testis, FOXL2 can also participate in the physiological regulation of endometrial tissue. Mutation of FOXL2 can cause small eyelid syndrome (BPES) and premature ovarian failure, so FOXL2 can be used as an important indicator of the prognosis and tumor progression of ovarian granulosa cell tumor, and it is also a specific marker of ovarian sex cord stromal tumor (SCST) Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molekulargewicht:

Calculated MW: 38 kDa

Observed MW: 50 kDa The actual band is not consistent with the expectation.

UniProt: O88470

Pathways: Nuclear Hormone Receptor Binding, Positive Regulation of Endopeptidase Activity