Rekombinanter EIF2S1 Antikörper

Produktnummer ABIN7828187

Der Kaninchen Monoklonal anti-EIF2S1 Antikörper wird verwendet zum Nachweis von EIF2S1 in Proben von Human, Maus und Ratte. Er wurde validiert für WB und IHC.

Kurzübersicht für Rekombinanter EIF2S1 Antikörper (ABIN7828187)

Target: EIF2S1 (Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser EIF2S1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Klon: A211

Produktdetails anti-EIF2S1 Antikörper

Verwendungszweck: Recombinant EIF2S1 Monoclonal Antibody

Aufreinigung: Protein A purified

Immunogen: Recombinant human EIF2S1 fragment

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000,IHC 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu EIF2S1

Target: EIF2S1 (Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1))

Andere Bezeichnung: EIF2S1

Hintergrund: EIF2S,EIF,EIF-2,EIF-2A,EIF-2alpha,EIF2,EIF2A,EIF2S1,EIF 2,EIF 2 alpha,EIF 2A,EIF 2alpha,EIF2 alpha,eIF-2-alpha,Eukaryotic translation initiation factor 2 subunit 1,Eukaryotic translation initiation factor 2 subunit 1 alpha,Eukaryotic translation initiation factor 2 subunit 1 alpha 35 kDa,Eukaryotic translation initiation factor 2 subunit alpha,IF2A,The eukaryotic translation initiation factor 2-α subunit (EIF2S1) is the first regulatory step that catalyzes the initiation of protein synthesis and promotes the binding of the initial tRNA to the 40S ribosomal subunit. As an important translation initiation factor, the eukaryotic initiation factor 2-α subunit is regulated by a variety of signal molecules, that is, it functions by regulating the phosphorylation and acetylation status of EIF2S1. Kinases activated by viral infection (PKR), endoplasmic reticulum stress (PERK/PEK), amino acid deprivation (GCN2) or heme deficiency (HRI) can phosphorylate EIF2S1 to regulate the transcription and translation of cell-related genes and enhance Cell protection mechanism. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molekulargewicht:

Calculated MW: 36 kDa

Observed MW: 36 kDa

UniProt: P05198

Pathways: Ribonucleoprotein Complex Subunit Organization, ER-Nucleus Signaling, Hepatitis C