Rekombinanter EPH Receptor A2 Antikörper

Produktnummer ABIN7828178

Der Kaninchen Monoklonal anti-EPH Receptor A2 Antikörper wird verwendet zum Nachweis von EPH Receptor A2 in Proben von Human. Er wurde validiert für WB und IHC.

Kurzübersicht für Rekombinanter EPH Receptor A2 Antikörper (ABIN7828178)

Target: EPH Receptor A2 (EPHA2)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser EPH Receptor A2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Klon: A213

Produktdetails anti-EPH Receptor A2 Antikörper

Verwendungszweck: Recombinant EphA2 Monoclonal Antibody

Aufreinigung: Protein A purified

Immunogen: Recombinant human EphA2 fragment

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000,IHC 1:200-1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu EPH Receptor A2

Target: EPH Receptor A2 (EPHA2)

Andere Bezeichnung: EphA2

Hintergrund: ARCC,CTPP,EPHA,Ephrin type-A receptor,CTRCT,ARCC2,CTPA,CTPP1,CTRCT6,ECK,EPHA2,Ephrin type-A receptor 2,Epithelial cell kinase,Tyrosine-protein kinase receptor ECK,AW545284,EPH receptor A2,Myk2,Sek2,Sek-2,Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Activated by the ligand ephrin-A1/EFNA1 regulates migration, integrin-mediated adhesion, proliferation and differentiation of cells. Regulates cell adhesion and differentiation through DSG1/desmoglein-1 and inhibition of the ERK1/ERK2 (MAPK3/MAPK1, respectively) signaling pathway. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molekulargewicht:

Calculated MW: 109 kDa

Observed MW: 130 kDa The actual band is not consistent with the expectation.

UniProt: P29317

Pathways: RTK Signalweg