Rekombinanter CD70 Antikörper

Produktnummer ABIN7828092

Der Kaninchen Monoklonal anti-CD70 Antikörper (Klon A550) (ABIN7828092) detektiert spezifisch CD70 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Rekombinanter CD70 Antikörper (ABIN7828092)

Target: CD70 (CD70 Molecule (CD70))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser CD70 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: A550

Produktdetails anti-CD70 Antikörper

Verwendungszweck: Recombinant CD70 Monoclonal Antibody

Aufreinigung: Protein A purified

Immunogen: Recombinant human CD70 fragment

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu CD70

Target: CD70 (CD70 Molecule (CD70))

Andere Bezeichnung: CD70

Hintergrund: Tumor necrosis factor ligand superfamily member,TNFSF,CD70,CD27-L,CD27L,CD27LG,TNFSF7,TNLG8A,CD27 ligand,CD70 antigen,Tumor necrosis factor ligand superfamily member 7,Ki-24,CD27L,TNFSF7,CD 27L,CD 70,CD27 L,CD27 LG,CD70 Molecule,Ki 24 antigen,Ki24 antigen,member 7,sCD27 Ligand,soluble CD27 Ligand,Surface antigen CD70,TNFSF 7,Tumor necrosis factor (ligand) superfamily,CD70 is a type II transmembrane glycoprotein and a member of the tumor necrosis factor ligand superfamily (TNFSF), also known as CD27L and TNFSF7. It is normally expressed on medullary thymic epithelial cells. Its expression is induced on activated lymphoid cells (B cells, T cells, and NK cells) and dendritic cells. CD70 is a ligand for CD27, a co-stimulatory receptor that plays an important role in T cell activation and proliferation. CD70 overexpression has been reported in various tumors such as renal cell carcinoma, glioblastoma, and non-small cell lung carcinoma and it's being actively pursued as a therapeutic target. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molekulargewicht:

Calculated MW: 23 kDa

Observed MW: 27,54,81 kDa The actual band is not consistent with the expectation.

UniProt: P32970

Pathways: Cancer Immune Checkpoints