Rekombinanter CD33 Antikörper
Kurzübersicht für Rekombinanter CD33 Antikörper (ABIN7828081)
Target
Alle CD33 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Recombinant CD33 Monoclonal Antibody
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Aufreinigung
- Protein A purified
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Immunogen
- Recombinant human CD33 fragment
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Isotyp
- IgG, kappa
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Applikationshinweise
- IHC 1:200-1:1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 mg/mL
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Buffer
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Haltbarkeit
- 12 months
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- CD33
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Andere Bezeichnung
- CD33
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Hintergrund
- CD33,SIGLEC-3,SIGLEC3,p67,CD33 Molecule,gp67,Myeloid cell surface antigen CD33,Sialic acid-binding Ig-like lectin 3,Siglec-3,CD33 Molecule,p67,SIGLEC3,Sialic-acid-binding immunoglobulin-like lectin (Siglec) that plays a role in mediating cell-cell interactions and in maintaining immune cells in a resting state. Upon engagement of ligands such as C1q or syalylated glycoproteins, two immunoreceptor tyrosine-based inhibitory motifs (ITIMs) located in CD33 cytoplasmic tail are phosphorylated by Src-like kinases such as LCK. These phosphorylations provide docking sites for the recruitment and activation of protein-tyrosine phosphatases PTPN6/SHP-1 and PTPN11/SHP-2. In turn, these phosphatases regulate downstream pathways through dephosphorylation of signaling molecules. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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UniProt
- P20138
Target
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