Rekombinanter CD276 Antikörper

Produktnummer ABIN7828078

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch CD276 in WB, FACS, IHC, IP und IF. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für Rekombinanter CD276 Antikörper (ABIN7828078)

Target: CD276

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser CD276 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)

Klon: A137

Produktdetails anti-CD276 Antikörper

Verwendungszweck: Recombinant B7-H3/CD276 Monoclonal Antibody

Aufreinigung: Protein A purified

Immunogen: Recombinant human B7-H3/CD276 fragment

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000,IHC 1:200-1:1000,IF 1:50,FCM 1:50-1:100,IP 1:25-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu CD276

Target: CD276

Andere Bezeichnung: B7-H3/CD276

Hintergrund: B7H,UNQ,PRO,B7-H,B7RP,B7 homolog,B7H34Ig-B7-H,PSEC,4Ig-B7-H,CD276,4Ig-B7-H3,B7-H3,B7H3,B7RP-2,B7 homolog 3,B7H34Ig-B7-H3,CD276 antigen,CD276 Molecule,Costimulatory molecule,PSEC0249,UNQ309,PRO352,B7RP-2,4Ig-B7-H3,B7H3,B7-H3,CD276 antigen,May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. Isoform 2 is shown to enhance the induction of cytotoxic T-cells and selectively stimulates interferon gamma production in the presence of T-cell receptor signaling. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molekulargewicht:

Calculated MW: 57 kDa

Observed MW: 110 kDa The actual band is not consistent with the expectation.

UniProt: Q5ZPR3

Pathways: Cancer Immune Checkpoints