Rekombinanter CPT1B Antikörper

Produktnummer ABIN7828065

Der Kaninchen Monoklonal anti-CPT1B Antikörper (Klon A672) (ABIN7828065) detektiert spezifisch CPT1B in WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Rekombinanter CPT1B Antikörper (ABIN7828065)

Target: CPT1B (Carnitine Palmitoyltransferase 1B (Muscle) (CPT1B))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser CPT1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Klon: A672

Produktdetails anti-CPT1B Antikörper

Verwendungszweck: Recombinant CPT1B Monoclonal Antibody

Aufreinigung: Protein A purified

Immunogen: Recombinant human CPT1B fragment

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: WB 1:1000-1:5000,IHC 1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu CPT1B

Target: CPT1B (Carnitine Palmitoyltransferase 1B (Muscle) (CPT1B))

Andere Bezeichnung: CPT1B

Hintergrund: KIAA,KIAA1670,CPT1B,CPT I,CPT1-M,CPTI-M,Carnitine palmitoyltransferase-1 (CPT1), localized to the mitochondrial outer membrane, translocates fatty acids across the mitochondrial membranes and catalyzes the rate-limiting step of β-oxidation. There are three isoforms of this enzyme: CPT1A (liver), CPT1B (muscle), and CPT1C (brain). Deficiency of CPT1A results in an autosomal recessive mitochondrial fatty acid oxidation disorder. Studies have shown that physiological high blood glucose and insulin levels inhibit CPT1B activity in human muscle and therefore divert long-chain fatty acids toward storage in human muscle as triglycerides. Furthermore, mice deficient in CPT1C show less food intake and reduced body weight. These findings suggest that CPT1 may play a role in metabolic syndromes. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molekulargewicht:

Calculated MW: 87 kDa

Observed MW: 87 kDa

UniProt: Q92523

Pathways: AMPK Signaling, Monocarboxylic Acid Catabolic Process