CPT1B Antikörper (Middle Region)

Produktnummer ABIN2782633

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CPT1B in WB und IHC. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Kaninchen, Rind (Kuh), Schaf und Zebrafisch (Danio rerio). Es wurde in 4+ Publikationen zitiert.

Kurzübersicht für CPT1B Antikörper (Middle Region) (ABIN2782633)

Target: CPT1B (Carnitine Palmitoyltransferase 1B (Muscle) (CPT1B))

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Kaninchen, Rind (Kuh), Schaf, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CPT1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-CPT1B Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: CPT1B Antibody - middle region

Sequenz: DLEMQFQRIL DDPSPPQPGE EKLAALTAGG RVEWAQARQA FFSSGKNKAA

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%, Zebrafish: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against CPT1B. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CPT1B

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46444-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-CPT1B Antikörper (ABIN2782633)

Fiserova, Trinh, Elkalaf, Vacek, Heide, Martinkova, Bechynska, Kosek, Hajslova, Fiser, Tousek, Polak: "Isoprenaline modified the lipidomic profile and reduced β-oxidation in HL-1 cardiomyocytes: In vitro model of takotsubo syndrome." in: Frontiers in cardiovascular medicine, Vol. 9, pp. 917989, (2022) (PubMed).

Jiang, Ma, Li, Cao, Wang, Zhang, Liu: "Effects of neonatal dexamethasone administration on cardiac recovery ability under ischemia-reperfusion in 24-wk-old rats." in: Pediatric research, Vol. 80, Issue 1, pp. 128-35, (2016) (PubMed).

Li, Liu, Ma, Guan, Cao, Tian, Zhang: "Enhancement of Glucose Metabolism via PGC-1α Participates in the Cardioprotection of Chronic Intermittent Hypobaric Hypoxia." in: Frontiers in physiology, Vol. 7, pp. 219, (2016) (PubMed).

Wolf-Johnston, Hanna-Mitchell, Buffington, Shinde, Roppolo, Mayer, Birder: "Alterations in the non-neuronal acetylcholine synthesis and release machinery in esophageal epithelium." in: Life sciences, Vol. 91, Issue 21-22, pp. 1065-9, (2012) (PubMed).

Details zu CPT1B

Target: CPT1B (Carnitine Palmitoyltransferase 1B (Muscle) (CPT1B))

Andere Bezeichnung: CPT1B

Hintergrund:

Background Information: The protein encoded by this gene, a member of the carnitine/choline acetyltransferase family, is the rate-controlling enzyme of the long-chain fatty acid beta-oxidation pathway in muscle mitochondria. This enzyme is required for the net transport of long-

Gene Name: Carnitine palmitoyltransferase 1B (muscle)

Alternative Symbols: CPTI, CPT1M, MCPT1, CPT1-M, CPTI-M, M-CPT1, MCCPT1

Protein Name: Carnitine O-palmitoyltransferase 1, muscle isoform

Molekulargewicht: 88 kDa

Gen-ID: 1375

NCBI Accession: NP_004368

UniProt: Q92523

Pathways: AMPK Signaling, Monocarboxylic Acid Catabolic Process