IL-9 Antikörper (AA 21-120)

Produktnummer ABIN740130

Dieses Anti-IL-9-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von IL-9 in WB, ELISA, IF (cc), IF (p), IHC (p) und IHC (fro). Geeignet für Maus. Dieses Primary Antibody wurde in 4+ Publikationen zitiert.

Kurzübersicht für IL-9 Antikörper (AA 21-120) (ABIN740130)

Target: IL-9 (IL9) (Interleukin 9 (IL9))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL-9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-IL-9 Antikörper

Bindungsspezifität: AA 21-120

Kreuzreaktivität: Maus

Homologie: Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse IL-9

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-IL-9 Antikörper (ABIN740130)

Yang, Li, Yang, Li: "Interleukin-9 Is Associated with Elevated Anti-Double-Stranded DNA Antibodies in Lupus-Prone Mice." in: Molecular medicine (Cambridge, Mass.), Vol. 21, pp. 364-70, (2016) (PubMed).

Lin, Zhang, Dai, Li, Wang, Zhang, Chen, Lu: "Expression of interleukin-9 and its upstream stimulating factors in rats with ischemic stroke." in: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, (2015) (PubMed).

Yao, Kong, Xie, Wang, Li, Liu, Sun, Li, Wang, Li, Qu, Zhao, Wang, Liu, Zhang, Mu, Li: "Neutralization of interleukin-9 ameliorates symptoms of experimental autoimmune myasthenia gravis in rats by decreasing effector T cells and altering humoral responses." in: Immunology, Vol. 143, Issue 3, pp. 396-405, (2014) (PubMed).

Details zu IL-9

Target: IL-9 (IL9) (Interleukin 9 (IL9))

Andere Bezeichnung: IL-9

Hintergrund:

Synonyms: P4, Il-9, Interleukin-9, Cytokine P4, T-cell growth factor P4, Il9

Background: The protein encoded by this gene is a cytokine that actsas a regulator of a variety of hematopoietic cells. This cytokinestimulates cell proliferation and prevents apoptosis. It functionsthrough the interleukin 9 receptor (IL9R), which activatesdifferent signal transducer and activator (STAT) proteins and thusconnects this cytokine to various biological processes. The geneencoding this cytokine has been identified as a candidate gene forasthma. Genetic studies on a mouse model of asthma demonstratedthat this cytokine is a determining factor in the pathogenesis ofbronchial hyperresponsiveness. [provided by RefSeq, Jul 2008].

Gen-ID: 16198

UniProt: P15247

Pathways: JAK-STAT Signalweg